| Charakter | Person |
|---|---|
| Mary Jane „MJ“ Watson | Rieke Werner |
| Miles Morales | Lars Waltl |
| Peter Parker / Spider-Man | Felix Mayer |
| Venom | Marios Gavrilis |
| Charakter | Person |
|---|---|
| Bürgermeister Norman Osborn | Kai Henrik Möller |
| Cletus Kasady / Carnage | Jean Paul Baeck |
| Dr. Otto Octavius / Doc Ock | Dirk Hardegen |
| Felicia Hardy / Black Cat | Lara „Loft“ Trautmann |
| Flint Marko / Sandman | Peter Sura |
| Harry Osborn | Nils Kreutinger |
| J. Jonah Jameson | Hanns-Jörg Krumpholz |
| Jefferson Davis | Michael-Che Koch |
| Lonnie Lincoln / Tombstone | Tobias Brecklinghaus |
| Mac Gargan / Scorpion | Michael-Che Koch |
| Martin Li / Mister Negative | Florian Hoffmann |
| Wilson Fisk / Kingpin | Thomas Balou Martin |
