| Rolle | Person |
|---|---|
| Aria T'Loak | Marion Elskis |
| Commander Shepard (Männlich) | Erik Schäffler |
| Commander Shepard (Weiblich) | Nicole Boguth |
| Der Unbekannte | Bernd Stephan |
| EDI | Christine Pappert |
| Garrus Vakarian | Ronald Spiess |
| Jack | Kathrin Spielvogel |
| Jacob Taylor | Holger Löwenberg |
| Jeff „Joker“ Moreau | Hubertus von Lerchenfeld |
| Legion | Stephan Schwartz |
| Miranda Lawson | Jennifer Böttcher |
| Mordin Solus | Jürgen Holdorf |
| Samara | Uta Delbridge |
| Tali'Zorah nar Rayya | Mia Diekow |
| Thane Krios | Konstantin Graudus |
| Zaeed Massani | Holger Mahlich |
| Rolle | Person |
|---|---|
| Admiral Daro'Xen vas Moreh | Angela Stresemann |
| Admiral Han'Gerrel vas Neema | Henry König |
| Admiral Shala'Raan vas Tonbay | Ulrike Johannson |
| Ashley Williams | ??? |
| Avina | Sonja Stein |
| Botschafter Donnell Udina | Henry König |
| C-Sicherheit-Zoll | Eva Michaelis |
| Captain Armando-Owen Bailey | Thomas Karallus |
| Captain David Anderson | Bernd Stephan |
| Dr. Karin Chakwas | Angela Stresemann |
| Elnora | Nicole Hannak |
| Emily Wong | Anne Moll |
| Glyph im DLC »Shadow Broker« | Martin Sabel |
| Grunt | Ole Jacobsen |
| Kaidan Alenko | Christian Rudolf |
| Kal'Reegar | Marc Seidenberg |
| Kasumi Goto | Djuwita Müller |
| Kelly Chambers | Marie Biermann |
| Kenneth Donnelly | Martin Sabel |
| Khalisah Al-Jilani | Christine Pappert |
| Kollektoren-General | Ben Hecker |
| Liara T'Soni | Tanja Dohse |
| Maelon | Tim Knauer |
| Matriarchin Aethyta | Katja Brügger |
| Morinth | Sonja Szylowicki |
| Rael'Zorah | Klaus Nietz |
| Schamane | Klaus Nietz |
| Urdnot Wreav | Douglas Welbat |
| Urdnot Wrex | Thomas Karallus |
| Vido Santiago | Eberhard Haar |