| Rolle | Person |
|---|---|
| Achilles Davenport | Jürgen Kluckert |
| Connor Kenway / Ratonhnhaké:ton | Dennis Schmidt-Foss |
| Desmond Miles | Thomas Friebe |
| Haytham Kenway | Dietmar Wunder |
| Juno | Claudia Gahrke |
| Minerva | Martina Treger |
| Rebecca Crane | Michaela Breit |
| Shaun Hastings | Philipp Schepmann |
| Rolle | Person |
|---|---|
| Abenteurer | Sven Hasper |
| Amanda Bailey | Andrea Aust |
| Animus-Stimme | Heike Hagen |
| Baptist | Klaus Lochthove |
| Benedict Arnold in den DLCs »Benedict Arnold« & »Die Tyrannei von König Washington« | Oliver Siebeck |
| Benjamin Church | Uwe Jellinek |
| Benjamin Franklin | Michael Nowka |
| Benjamin Tallmadge | Oliver Rohrbeck |
| Bernardo de Gálvez / „Der Gouverneur“ | Matti Klemm |
| Catherine | Arianne Borbach |
| Catherine Kerr | Bianca Krahl |
| Charles Lee | Till Hagen |
| Corrine | Ulrike Lau |
| Cutter | Wolfgang Wagner |
| Cyrus | Matti Klemm |
| Daniel Cross | Julius Jellinek |
| David „Big Dave“ Walston | Bernd Rumpf |
| David Clutterbuck | Wolfgang Wagner |
| Deborah „Dobby“ Carter | Arianne Borbach |
| Der Commander | Oliver Rohrbeck |
| Diana | Tina Haseney |
| Doktor | Joachim Tennstedt |
| Dr. Lyle White | Norman Matt |
| Dr. Warren Vidic | Rainer Delventhal |
| Duncan Little | Volker Wolf |
| Duncan McGill / „Der Highlander“ | Till Hagen |
| Edward Braddock | Tilo Schmitz |
| Ellen | Bianca Krahl |
| Emily Burke / „Die Pionierin“ | Yvonne Greitzke |
| George Washington | Reinhard Kuhnert |
| Gillian McCarthy / „Die Verführerin“ | Bianca Krahl |
| Godfrey | Oliver Rohrbeck |
| Harold Ring | Michael Nowka |
| Hinkebein | Markus Pfeiffer |
| Israel Putnam | Andreas Müller |
| Jacob Zenger | Tobias Kluckert |
| Jaime Colley | Michael Hansonis |
| James | Karlo Hackenberger |
| James Barrett | Stefan Gossler |
| John Anderson | Baki Davrak |
| John Fitzwilliams | Matti Klemm |
| John Fraser | Joachim Tennstedt |
| John Parker | Volker Wolf |
| John Pitcairn | Helmut Gauß |
| Kahionhaténion | Matti Klemm |
| Kanen'tó:kon | Karlo Hackenberger |
| Kaniehtí:io | Tanya Kahana |
| Kapitän | Tilo Schmitz |
| Kutscher | Patric Tavanti |
| Lance | Klaus Lochthove |
| Louis Mills | Florian Halm |
| Lyle White | Norman Matt |
| Marquis de Lafayette | Martin Nunez |
| Mason Weems | René Dawn-Claude |
| Matrose Louis Mills | Florian Halm |
| Mr. Harrison | Fritz Rott |
| Mr. Little | Oliver Siebeck |
| Myriam | Debora Weigert |
| Nicholas Biddle | Joachim Kaps |
| Norris / Maurice | Martin Kautz |
| Nukilik / „Der Starke Mann“ | Till Hagen |
| Oliver | Udo Schenk |
| Patrick O'Hara | Jan Andres |
| Paul Revere | Charles Rettinghaus |
| Peter Bunyon | Uwe Büschken |
| Prediger | Jürgen Kluckert |
| Prudence | Iris Artajo |
| Quincent | Gregor Höppner |
| Radio-Sprecher | Matti Klemm |
| Reginald Birch | Jochen Schröder |
| Richard Clutterbuck | Johannes Berenz |
| Robert Faulkner | Axel Lutter |
| Rupert Martin | Udo Schenk |
| Samuel Adams | Detlef Bierstedt |
| Samuel Prescott | Udo Schenk |
| Schiffsarzt | Joachim Tennstedt |
| Silas Thatcher | Uwe Büschken |
| Stadtschreier | Jan Kurbjuweit |
| Stéphane Chapeau | Stefan Krause |
| Tavernenspieler | Michael Pan |
| Terence „Terry“ | Marcel Collé |
| Thomas Hickey | Matti Klemm |
| Vater Timothy | Uwe Büschken |
| Victor Wolcott / „Der Quacksalber“ | Florian Halm |
| Warren | Richard Barenberg |
| William Johnson | Lutz Riedel |
| William Miles | Bodo Wolf |
| William Molineux | Joachim Tennstedt |