| Rolle | Person |
|---|---|
| Commander Shepard (Männlich) | Erik Schäffler |
| Commander Shepard (Weiblich) | Nicole Boguth |
| EDI | Christine Pappert |
| Garrus Vakarian | Ronald Spiess |
| James Vega | Jan-David Rönfeldt |
| Javik | Frank Felicetti |
| Jeff „Joker“ Moreau | Hubertus von Lerchenfeld |
| Kaidan Alenko | Christian Rudolf |
| Liara T'Soni | Tanja Dohse |
| Tali'Zorah nar Rayya / Tali'Zorah vas Normandy | Mia Diekow |
| Rolle | Person |
|---|---|
| Admiral Daro'Xen vas Moreh | Angela Stresemann |
| Admiral Han'Gerrel vas Neema | Henry König |
| Admiral Shala'Raan vas Tonbay | Ulrike Johannson |
| Admiral Zaal'Koris vas Qwib Qwib | Gustav Adolph Artz |
| Aria T'Loak | Marion Elskis |
| Ashley Williams | Isabella Bartdorff |
| Avina | Sonja Stein |
| Balak | Joscha Fischer-Antze |
| Barla Von | Eberhard Haar |
| Botschafter Dominic Osoba | Uli Pleßmann |
| Captain Armando-Owen Bailey | Thomas Karallus |
| Captain David Anderson | Rainer Schmitt |
| Cerberus-Propaganda-Sprecher (Grissom-Akademie) | Gustav Adolph Artz |
| Chefingeneur Gred Adams | Oliver Böttcher |
| Conrad Verner | Stefan Brentle |
| Das Kind | Lasse Crohn |
| David Archer | Oliver Böttcher |
| Der Unbekannte | Bernd Stephan |
| Diana Allers | Kristina von Weltzien |
| Dorn'Hazt vas Rannoch | Marc Seidenberg |
| Dr. Chloe Michel | Freya Trampert |
| Dr. Gavin Archer | Lennardt Krüger |
| Dr. Karin Chakwas | Isabella Grothe |
| Glyph | Martin Sabel |
| Grunt | Ole Jacobsen |
| Henry Lawson | Joscha Fischer-Antze |
| Jack | Kathrin Spielvogel |
| Kahlee Sanders | Ulrike Johannson |
| Kai Leng | Torsten Michaelis |
| Kasumi Goto | Djuwita Müller |
| Kelly Chambers | Marie Biermann |
| Kenneth Donnelly | Martin Sabel |
| Khalisah Al-Jilani | Marie Biermann |
| Legion | Stephan Schwartz |
| Major Coats | Guido Zimmermann |
| Major Kirrahe | Kai Henrik Möller |
| Matriarchin Aethyta | Katja Brügger |
| Miranda Lawson | Jennifer Böttcher |
| Mordin Solus | Jürgen Holdorf |
| Primarch Adrien Victus | Uli Pleßmann |
| Protheanische VI Vendetta | Frank Felicetti |
| Rachni-Königin | Ole Jacobsen |
| Ratsherr Donnell Udina | Henry König |
| Samantha Taylor | Simona Pahl |
| Samara | Uta Delbridge |
| Schamane | Joscha Fischer-Antze |
| Septimus Oraka | Joscha Fischer-Antze |
| Steve Cortez | Leonhard Mahlich |
| Steven Hackett | Eberhard Haar |
| Tarquin Victus | Samuel Weiss |
| Thane Krios | Konstantin Graudus |
| Urdnot Wreav | Douglas Welbat |
| Urdnot Wrex | Thomas Karallus |
| Zaeed Massani | Holger Mahlich |
